We develop new imaging methods, computational models and visualization tools to ‘make visible’ critical aspects of cancer, stroke and neurobiology.
We characterize the disease 'microenvironment’ by developing novel imaging approaches and using these imaging data in computational applications that facilitate development of new clinical biomarkers and tools that enable a deeper understanding of disease progression, and response to therapy. For example, in cancer we have developed new imaging methods for characterizing changes in the tumor microenvironment and the pathways involved in metastasis. Although originally focused on cancer, innovations from our lab are now being adopted to answer questions in the neurosciences and diseases such as stroke. Our research broadly encompasses the following areas: